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The Lancet Infectious Diseases

The Lancet Infectious Diseases is another prestigious publication from the Lancet family of journals. After our success with the Lancet Oncology covers we were invited to pitch, and won the contract for the Lancet Infectious Diseases cover illustrations.

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Effects of Maternal Infections on Children’s Immune System (Vol 12 – Issue 4)

In most cases, the articles that inspire the Lancet front covers can be concentrated down to single visual concepts. This helps create images with maximum impact. On this occasion, the article inherently had a multifaceted concept that would need to be depicted in its entirety without reduction in complexity. Namely, the article discussed the effects on an unborn child’s immune system if the mother was chronically infected during the pregnancy. To achieve this we created a foetus in the womb and added some antibodies in the foreground – the child’s immune system. Then to depict a chronic infection of the mother during the pregnancy, we created a port-hole view, where the three trimesters were shown, surrounded by viruses at all stages. The general port hole feel of the image was pleasing, had depth and covered the concept in its entirety.

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Surgical Resection for Drug-Resistant Tuberculosis (Vol 12 – Issue 2)

Surgical resection as an adjuvant treatment for drug-resistant tuberculosis was the theme that needed illustrating for this month’s cover illustration of The Lancet Infectious Diseases. A pair of lungs dominated the cover. We added a diseased part of the lungs on the left and added a dashed line around it to symbolise surgical resection. To suggest the drug resistant part of the concept, we added a background of tuberculosis bacteria (Mycobacterium tuberculosis) happily laying on capsules and pills.

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Global Rabies Elimination (Vol 12 – Issue 5)

Rabies was the subject to be illustrated for this issue. With recent covers showing the ‘disease culprits’, we were keen to take another route for this illustration to keep things mixed up and fresh. We opted for a bold conceptual image based on the international biohazard symbol. To suggest that rabies was the biohazard in question, we added dog prints to the symbol as dog bites are overwhelmingly the most common cause of rabies in humans.

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Human Immunodeficiency Virus – HIV (Vol 12 – Issue 7)

HIV was the focus of several articles in issue 7, so to encompass them all in a single image, the HIV viron itself was chosen for the illustration. The model of the HIV viron was carefully created so that is was scientifically accurate whilst also visually impressive. The phospholipid membrane that makes up the main spherical shape can be clearly seen (there are hundreds of thousands of the individual elements!). We also added the various surface proteins and the main viral spikes (trimers of gp120 on gp41 stalks).

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