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Gastrointestinal Mode-of-Action Animation

Targeted Treatment of C. difficile Infection (CDI) with Fidaxomicin

Two animations taken from a recent project for Tillotts Pharma AG.  This project highlights the significant issue of C. difficile infection (CDI) and the need for a targeted response.  A targeted response is necessary to avoid the paradox where broad spectrum antibiotics affect both the CDI and adversely affect the natural gut microbiome leading to an increased chance of CDI recurrence. 
You can find the full project in "Our Work" area.


Spore Germination

C. difficile is typically ingested in its spore form.  Once injested, the spores enter the small intestine where they germinate into the vegetative form which subsequently enters the colon where it exerts its negative effects.

Toxin Damage

When C. difficile enters the colon, it releases two toxins which cause damage to the colonic mucosa and inflammation.

Medical Journal Illustrations

Animated Healthcare was selected to produce the cover images for
The Lancet Diabetes & Endocrinology 2024

Lancet Covers 02.jpg
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